Edin Botan1, Metin Ay2, Merve Boyraz2, Derya Bako3, Servet Yüce4

1T.C. Sağlık Bilimleri Üniversitesi, Van Eğitim Araştırma Hastanesi, Çocuk Yoğun Bakım Ünitesi, Van, Türkiye
2T.C. Sağlık Bilimleri Üniversitesi, Van Eğitim Araştırma Hastanesi, Çocuk Sağlığı Ve Hastalıkları, Van, Türkiye
3T.C. Sağlık Bilimleri Üniversitesi, Van Eğitim Araştırma Hastanesi, Çocuk Radyoloji Bilim Dalı, Van, Türkiye
4İstanbul Üniversitesi İstanbul Tıp Fakültesi, Halk Sağlığı Anabilim Dalı, İstanbul, Türkiye

Keywords: mis-c, COVID-19, neurological, complication


COVID-19 has seriously affected children and the whole world. Pediatric multi-system inflammatory syndrome (MIS-C), a new syndrome that has not been known before, has been described. Although MIS-C may progress with different clinical manifestations in children, neurological involvement is reported relatively rarely. A 12-year-old girl with cerebral palsy and motor mental retardation was admitted to the emergency department with complaints of cough, fever, mouth sores and malnutrition. As a result of the evaluation, the patient was hospitalized to investigate the etiology of the fever and empirical antibiotic treatment was started, and she developed a rash on the 3rd day and tonic-clonic convulsions on the 5th day. The patient was hospitalized in the pediatric intensive care unit (PICU), and COVID-19 IgG and IgM were positive. Cerebral imaging of the patient was reported as normal. The patient with fever, rash, convulsions lasting longer than five days, and compatible laboratory results were diagnosed with MIS-C. Intravenous immunoglobulin (IVIG) and methylprednisolone treatments were started, and the patient was discharged on the 14th day of hospitalization, whose condition improved. This case is presented as an example of the rare neurological involvement of MIS-C. Detailed clinical investigation and neurological examination are required to exclude neurological sequelae of COVID-19 during the pandemic. The development of general guidelines that can combine them would be instructive.

Cite this article as: Botan E, Ay M, Boyraz M, Bako D, Yuce S. Neurological Complications in MIS-C: Case Report. Pediatr Acad Case Rep. 2023;2(2):49-52.

Conflict of Interest

The authors declared no conflicts of interest with respect to authorship and/or publication of the article.

Financial Disclosure

The authors received no financial support for the research and/or publication of this article.