Seyran Bulut1, Zeki Beyzade2, Mutluhan Yiğitaslan2, Rabia Meral1, Eren Er1, Bumin Dündar3

1Tepecik Training And Research Hospital, Pediatric Endocrinology, İzmir, Turkiye
2Tepecik Traininng And Research Hospital, Pediatric Clinic, İzmir, Turkiye
3Katip Celebi University , Pediatric Endocrinology, İzmir, Turkiye

Keywords: İnsulin, edema, type 1 DM


Insulin is the essential hormone in managing Type 1 Diabetes Mellitus (DM). Severe complications can be seen during treatment. Insulin-dependent edema is a rare complication that can be seen regularly in patients with new diagnoses or poorly controlled diabetes shortly after the start of intensive insulin therapy. It can present itself in various clinical forms, from minimal peripheral edema to heavy pericardial, pleural edema and even heart failure. Although insulin-dependent edema has been known for a long period, the number of cases reported in the literature is very few. We are reporting four cases with poorly controlled type 1 diabetes that developed insulin edema.

Cite this article as: Bulut S, Beyzade Z, Yigitarslan M, Meral R, Er E, Dundar B. The rare complication of type 1 DM, which is insulin-dependent edema: Four patient case reports presenting with the same clinical manifestation. Pediatr Acad Case Rep. 2023;2(1):12-5.

Conflict of Interest

The authors declared no conflicts of interest with respect to authorship and/or publication of the article.

Financial Disclosure

The authors received no financial support for the research and/or publication of this article.