Pediatric Peptic Ulcer Resulting in Massive Upper Gastrointestinal Bleeding: A Case Report with Clinical Management Insights

Kenly Chandra1, Magdalena Kristi Daradjati Saudale2, Christy Venada3

1Sito Husada Hospital, General Practitioner, Atambua, East Nusa Tenggara, Indonesia
2Sito Husada Hospital, Department Of Child Health, Atambua, East Nusa Tenggara, Indonesia
3Atma Jaya Catholic University Of Indonesia, Faculty Of Medicine And Health Science, Jakarta, Indonesia

Keywords: Upper gastrointestinal bleeding, peptic ulcer disease, pediatric endoscopy, case report

Abstract

Pediatric peptic ulcer disease (PUD) resulting in massive upper gastrointestinal bleeding (UGIB) is an uncommon yet critical condition that necessitates prompt and targeted intervention. We present a case of a 16-year-old female with severe hematemesis, melena, and hemodynamic instability, ultimately diagnosed with a duodenal ulcer via endoscopy. Initial resuscitation involved intravenous fluids, blood transfusions, proton pump inhibitors (PPIs), and tranexamic acid, followed by definitive hemostasis via endoscopic hemoclipping. This case underscores the significance of early recognition, timely resuscitation, and appropriate endoscopic intervention in managing pediatric UGIB. A literature review was conducted to contextualize the clinical approach, highlighting optimal treatment strategies in resource-limited settings. This case contributes to the growing body of knowledge on pediatric UGIB and provides clinically practical insights for improving patient outcomes.

Cite this article as: Chandra K, Daradjati Saudale MK, Venada C. Pediatric Peptic Ulcer Resulting in Massive Upper Gastrointestinal Bleeding: A Case Report with Clinical Management Insights. Pediatr Acad Case Rep. 2025;4(3):46-51.

Conflict of Interest

The authors declared no conflicts of interest with respect to authorship and/or publication of the article.

Financial Disclosure

The authors received no financial support for the research and/or publication of this article.